The most frequent DNA lesions (8-oxoguanine, thymine glycol, dihydrothymine, dU) (De Bont and van Larebeke, 2014) are removed from the genome by the BER (Kim and Wilson, 2012) (Figure 1). This repair ...

Base excision repair (BER) is a fundamental pathway that safeguards genomic integrity by detecting and removing small base lesions arising from oxidation, alkylation, deamination or spontaneous base ...

Effects of TKI on patients with non-small cell lung cancer of different stages: A meta-analysis. This is an ASCO Meeting Abstract from the 2018 ASCO Annual Meeting I. This abstract does not include a ...

DNA is the instruction manual for every living organism, guiding the development and functioning of all biological processes. In essence, it is a molecule with a double helix structure with each unit ...

A new study by researchers from the Gwangju Institute of Science and Technology in the Republic of Korea has revealed the mechanism of DNA repair by enzymes exonuclease III and polymerase I by ...

A researcher has made a discovery that alters our understanding of how the body's DNA repair process works and may lead to new chemotherapy treatments for cancer and other disorders. Researchers ...

Role of T0 status in overall survival for unresectable stage III non-small cell lung cancer. Detection of early-stage lung cancer by exhaled volatile organic compounds using a high-pressure photon ...