Researchers have reversed memory loss in aging mice by targeting a protein that builds up in brain cells, pointing toward a potential pathway to counter the cognitive declines of aging. In a new study ...

One in three families knows someone living with memory loss, and late-onset Alzheimer’s disease affects tens of millions worldwide. The strongest common genetic risk factor is APOE: the E4 isoform ...

A protein called ferritin light chain 1 (FTL1) may play a significant role in brain aging, a new study reveals, giving scientists a new target for understanding and potentially preventing brain ...

Cedars-Sinai researchers created “young” immune cells from human stem cells that reversed cognitive decline and Alzheimer’s symptoms in mice. The treated animals showed better memory and healthier ...

Memories are thought to be stored in sparse groups of neurons called engrams. These are the cells that switch on during learning and can later switch on again during recall. In physiological aging and ...

Age-related changes in protein tagging and degradation may help explain how the brain declines over time and why diet can still influence these processes.

A protein named after a Greek goddess is reshaping how scientists think about cognitive decline — and it turns out the brain doesn't just age passively. It negotiates with aging every day, through ...

Researchers have identified two brain receptors that help the brain clear away amyloid beta, a hallmark of Alzheimer’s disease. By stimulating these receptors in mice, scientists increased levels of a ...

After treatment, the mice’s memories were essentially shunted back into a younger state. The researchers found that reprogrammed engrams displayed molecular behavior of more youthful cells. Using a ...

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible. But the brain is not static; neurons continually adjust the strength of their ...