Two papers published in Nature describe the structure and conformation of myosin in the cardiac thick filaments and how it interacts with other thick-filament proteins, such as titin and cardiac ...

Contraction of the heart is driven by cyclical interactions between myosin and actin filaments powered by ATP hydrolysis. The modular structure of heart muscle and the organ-level synchrony of the ...

It's been estimated that over one lifetime, a heart will beat 2.5 to 3 billion times without stopping. Yet the mechanics of how the heart physically carries out this function flawlessly, without fail, ...

Researchers have characterised changes in the structure of motor proteins, called myosins, and energy consumption that occur during hibernation, highlighting key differences in large and small ...