Researchers have found that a carefully orchestrated act of X-chromosome 'yoyo' predicts the successful and efficient development of mammalian egg cells. The findings could pave the way for generating ...

Since December 2022, the nationwide control policy on the COVID-19 epidemic has been changed in China. Fertility and in vitro fertilization (IVF) centers are receiving increasing numbers of infected ...

This study provides valuable insights into the role of MATR3 in oocyte maturation and folliculogenesis, using conditional knockout mice and in vitro follicle culture systems to show that MATR3 is ...

When the female germline develops, oocyte growth is accompanied by many changes in gene expression, however, the regulatory networks that control this process have not been determined. Now, a group of ...

A multi-institutional team of ovarian biologists and other reproductive specialists reports that putting an oocyte from an older mouse into the follicle of a young mouse can rejuvenate the oocyte, ...

The new method offers researchers a powerful new platform to investigate the molecular mechanisms that control oogenesis, the process by which egg cells develop, and lays important groundwork for ...

Declining female fertility is a health issue that has received broad global attention. Oocyte quality is the key limiting factor of female fertility, and factors affecting oocyte quality involve the ...

In a new study published in the journal Nature, researchers in Japan report that activating just eight genes for producing gene-controlling proteins is enough to convert mouse stem cells directly into ...

Oocytes are immature egg cells that develop in almost all female mammals before birth. The propagation of future generations depends on this finite reserve of cells surviving for many years without ...